Fundamentals of Dry Granulation and Roller Compaction Technology

In this paper, we are going to discuss about the fundamentals of dry granulation and roller compaction technology. The process of granulation forms the main part of this paper.

The process of granulation involves the adhering of various powder particles together to form granules. It is the procedure that helps to create bond between the particles that helps in manufacturing of tablets and other forms of medicines in the pharmaceutical industry. Along with the wet granulation process, dry granulation has gained much importance in this industry. It is the process that doesn’t involve any use of liquid in the procedure. 

With the exertion of some pressure the powder gets compacted, which also causes magnification in its size. The acquired compact is in the form of ribbons or flakes. The whole process is then followed by the milling process to get the desirable granules.

Fundamentals of the process

In order to get the desirable granules, two methods are generally used in the process of dry granulation. 

• Slugging
• Roller compaction

The process that involves the use of tablet press is known as slugging. Because of the great difference in the weight of elements that is caused during the process, variations can be seen in the properties of the granules. For this reason, this process is not in use now-a-days.

Whereas, roller compaction is greatly used as it maintains the weight and the properties of the granules. Three chief units make up the roller compaction machine:

1. Firstly, the feeding unit, which helps to pass on the powder to the compaction part that is between the rolls.
2. The second unit is the compaction unit. This is where the powder gets compacted, with the help of two rollers that are constantly rotating against each, into thin ribbons.
3. And lastly, the size reduction unit. In this section, the ribbons go through the milling process that helps to get the desirable sized granules.

Parts of the Roller compaction machine

The compaction machinery generally consists of the following parts:

• Inlet funnel with an agitator
• Feed auger
• Tamp auger
• Inlet funnel that holds small quantity
• Press rollers with ribbons
• Rotor with preferred granules

Product Superiority Features

In this process pressure is being exerted on the two rollers to get the desired compacted granules. The unit of the force that is applied in this machine is force per cm, expressed as kN/cm. Certain amount of the force is applied on the ribbons, which of course depends on the quantity of the powder used.

The roller compactors are generally used in two types. One consists of a fixed gap in the rollers while the other has got floating gaps that can be adjusted accordingly. Among these two types the second one is more convenient as it helps to maintain the properties of the granules. 

The process of Milling

Just after the compaction process is carried on, the milling of the ribbons is done. In this process a screen is used which helps to maintain the granule size.

Application

With the help of this dry granulation process the density and property of the granules can be maintained. The result of using it is the better flow of materials along with increasing the size of the particles. Moreover, the compaction process prevents the granules from getting segregated and thus helps to maintain the uniformity of the dosages.

Conclusion 

Dry Granulation and Roller Compaction technology has helped the Pharmaceutical industry in a great many ways. With the low running cost and the high efficiency it has proved its worth in the industry.

Author Bio
The author Jayesh Khambhayata in this article has explained about the fundamentals of Dry granulation and roller compaction technology that are used as pharmaceutical machinery and pharmaceutical equipment in the industry. Cemach Machineries has brought about the latest form of these machineries for the help of the industry.

The role of the roll forming machines in our daily life

We have the necessity to use more developed machines as to accomplish our duties as fast as possible. The life we live requires a lot of machines for the easy convenience. Have you ever paid a thought over how all the machines we use in our daily life are manufactured? They are also made with the help of a machine. They are called Roller Compactor machine. Roll forming machines build up different kinds of machines that lend help to manufacture those machines which are an integral part of our advanced life style. To enhance the advantages of your life Roller Compactor industry is presenting you with most advanced and innovative technology.

The Roll Compactor companies that produce such machines hold the CE certificate for that. There are different kinds of machines are manufactured in the industry of Roll Compactor machine. The kinds of Roll Compactor machines are steel purling roll forming machines, stud and track roll forming machines, slitting and cut to length machines, etc. each of the machines come with 2 years or 550 working hours guarantee. IBR sheet roll forming machine is one of them. It has a great value in our daily day life. In the modern life, it is completely unthinkable to live a life without it. It is mainly used in the African market. There are two kinds of IBR sheet former machines and they are IBR686 and IBR890. Whatever we do we need the help of papers and sheets to ensure an agreement of for the sake of fast communication, the help of the sheets is inevitable. To make the sheets there is a sheer need for Roll Compactor Machine and to manufacture them there is a need for machines that create them. To meet the demand, there is a need for such a Machine that would lend help to manufacture them. But what is so important in this matter is to manufacture in a creative and innovative way. It is completely capable of providing that.

The body of the machines is generally created with 36 A3 H beam steel, 45# steel is the materials that are commonly used in the manufacture of the machines. Only materials are not the necessary rather there are other needs for them as to provide enough amount of heat equally important. After they are sent to chroming treatment. Black oxide or blackening treatment is usually provided immediately after the manufacture of the machines. In the industry of Pharmaceutical Machineries, there is a great need of other developed machines which are imported from China basically. Not all kinds of machines and equipment can be helpful in this matter. So the helping machines are picked out carefully.

Summary:

Roll forming machines are huge help making different kinds of machines and to produce innovative and technologically advanced machines to help increase the convenience of life.

Roll Equipments Used For Making Smooth Surface

Different equipments are used for constructing highways and making leveled surface. For constructing road, Roll compactor is used which is very important for compaction process. Due to its process, road quality becomes good. These equipments must be handled very carefully.

What is the purpose of compactors?

Compactor is a machine used in constructing road and removing the waste material through compaction process. Roll compactor is basically used by home owners and businessman. Compactor can take different shape and size means it is very variable. Different types of compactors are used for different things like bulldozer or also called landfill compactor equipment removes and drives onto waste, also it collect waste materials through plates from different areas. Compactors are operated hydraulically and thus it is very easy to operate it. It also used for picking up the trashed cars, etc. Roll compactors are used for reducing the waste through compaction and compression process.

How compactors processed in making road?

Roller compactors play a very big part in the compaction process. It is the first that many constructors used for gripping the soil. The drum roller compactor is used for compressing the soil level so that road can be constructed and it makes the surface level equal and thus ground become even, providing maximum effectiveness. Next graders are used for making the road base and it is compacted using roll drums. The last step is making the pitch level of the road using paver that makes the surface smooth. The pitch level is compacted by roll drum and thus, the road is ready for vehicles.

Different types of machineries used in construction

There are mostly two pharmaceutical machinery are used for constructing road first is pedestrian roll and second is smooth rolls that give finishing roads. It basically used vehicle weight for compression and compaction of different materials. Some machinery consists of heavy drums and large size of wheels that make the surface level smooth and equal.

Find different varieties and designs of compactor devices

Roller compactor comes in different designs, colors, sizes, weights, etc depending on the surface compaction. The pedestrian machinery is used for constructing roads for walking people. In construction of it, many workers are required, which pushes or pull the machine when material compresses and the machine moves above the surface. These types of machine are either automatically operated by power or it consists of an engine which is filled either by gas or diesel. Different pharmaceutical machinery is reverse or forward plate compactor, etc.

Grab the benefits of using machinery in pharmaceutical industry

Smooth pharmaceutical machinery are operated through power or by diesel engine in which the worker can sit on the seat and operate it from there and thus it does not require laborers for pushing or pulling the machine. It consists of different types of drum that give finishing smoothness like single drum or vibrating drum, etc. thus, these machineries are used by many renowned companies for construction.

Tablet Press Machine - Work and Application

What is a press? Press is a machine that presses any material into a specific design, shape and size. It has dies and punches. The die gives the specific design (shape) and punch presses to give size to the product. Press has a very wide field of application. One of them is pharmaceutical industry.

Press Machine in Pharmaceutical Industry-

Press machines are used in the pharmaceutical industry to make tablets. Press machines can be used to manufacture tablets of drugs. The mechanical device that compresses powder into tablet of uniform weight and size is known as press machine. A tablet machine can produce about 250000 tablets an hour.

How to form a tablet?

To form a tablet, a fine powdered material of pre determined amount must be poured into the cavity formed by two punches and die. After this the punches must be press against each other with a great force to fuse the powdered material.

Tablet Press Machine

Working of Tablet Press Machine-

The tablet press machine is also known as Tablet Machine. Since the principle of compression is used by the machine to make tablets, the machine is also called as Tablet Compression Machine. Operation of the tablet press machine is as follows-

First of all the bottom punch moves down the die i.e. lowered upto a depth. The fine powdered material is fed into the cavity by a lead screw and the hopper charger. The amount of powder is equal to or may be less than the depth of the bottom punch. If the level of the powder increases then a scrapper is provided which removes extra amount of material. Once the feeding of powdered material is done the upper comes in contact with the powder. The upper punch covers the die.

The next operation is the compression operation. The large force that needs to be applied to compress the material inside the die is done by the high pressure compression rolls (rollers). The force the powdered material to fuse together into tablet.

After compression operation is done the bottom punch is raised above to eject out the tablet. In other words it’s just a spill off process.

Types of Tablet Press Machines-
The development of the machine industry has led to different types of tablet machines. They are classified into two categories. They are Single Punch Tablet Machines and Rotary Tablet Press Machines.

In order to increase the production and minimise the time required to manufacture tablets rotating tablet press were invented. The high speed tablet press machines today are rotary tablet press. They have a rotating turret comprising of a number of pumches. As the turret rotates the punches come in contact with cams that control their vertical position. The rotation, the position of dies and punches are easily customised depending upon the requirements of the tablet size and shape.

Hence the tablets that we come across in our day to day lives are manufactured by simple process of compression by "Tablet Press Machines". Tablets may be of anything like drug or any other material; they are manufactured in the same simple way.