Fundamentals of Dry Granulation and Roller Compaction Technology

In this paper, we are going to discuss about the fundamentals of dry granulation and roller compaction technology. The process of granulation forms the main part of this paper.

The process of granulation involves the adhering of various powder particles together to form granules. It is the procedure that helps to create bond between the particles that helps in manufacturing of tablets and other forms of medicines in the pharmaceutical industry. Along with the wet granulation process, dry granulation has gained much importance in this industry. It is the process that doesn’t involve any use of liquid in the procedure. 

With the exertion of some pressure the powder gets compacted, which also causes magnification in its size. The acquired compact is in the form of ribbons or flakes. The whole process is then followed by the milling process to get the desirable granules.

Fundamentals of the process

In order to get the desirable granules, two methods are generally used in the process of dry granulation. 

• Slugging
• Roller compaction

The process that involves the use of tablet press is known as slugging. Because of the great difference in the weight of elements that is caused during the process, variations can be seen in the properties of the granules. For this reason, this process is not in use now-a-days.

Whereas, roller compaction is greatly used as it maintains the weight and the properties of the granules. Three chief units make up the roller compaction machine:

1. Firstly, the feeding unit, which helps to pass on the powder to the compaction part that is between the rolls.
2. The second unit is the compaction unit. This is where the powder gets compacted, with the help of two rollers that are constantly rotating against each, into thin ribbons.
3. And lastly, the size reduction unit. In this section, the ribbons go through the milling process that helps to get the desirable sized granules.

Parts of the Roller compaction machine

The compaction machinery generally consists of the following parts:

• Inlet funnel with an agitator
• Feed auger
• Tamp auger
• Inlet funnel that holds small quantity
• Press rollers with ribbons
• Rotor with preferred granules

Product Superiority Features

In this process pressure is being exerted on the two rollers to get the desired compacted granules. The unit of the force that is applied in this machine is force per cm, expressed as kN/cm. Certain amount of the force is applied on the ribbons, which of course depends on the quantity of the powder used.

The roller compactors are generally used in two types. One consists of a fixed gap in the rollers while the other has got floating gaps that can be adjusted accordingly. Among these two types the second one is more convenient as it helps to maintain the properties of the granules. 

The process of Milling

Just after the compaction process is carried on, the milling of the ribbons is done. In this process a screen is used which helps to maintain the granule size.

Application

With the help of this dry granulation process the density and property of the granules can be maintained. The result of using it is the better flow of materials along with increasing the size of the particles. Moreover, the compaction process prevents the granules from getting segregated and thus helps to maintain the uniformity of the dosages.

Conclusion 

Dry Granulation and Roller Compaction technology has helped the Pharmaceutical industry in a great many ways. With the low running cost and the high efficiency it has proved its worth in the industry.

Author Bio
The author Jayesh Khambhayata in this article has explained about the fundamentals of Dry granulation and roller compaction technology that are used as pharmaceutical machinery and pharmaceutical equipment in the industry. Cemach Machineries has brought about the latest form of these machineries for the help of the industry.

The role of the roll forming machines in our daily life

We have the necessity to use more developed machines as to accomplish our duties as fast as possible. The life we live requires a lot of machines for the easy convenience. Have you ever paid a thought over how all the machines we use in our daily life are manufactured? They are also made with the help of a machine. They are called Roller Compactor machine. Roll forming machines build up different kinds of machines that lend help to manufacture those machines which are an integral part of our advanced life style. To enhance the advantages of your life Roller Compactor industry is presenting you with most advanced and innovative technology.

The Roll Compactor companies that produce such machines hold the CE certificate for that. There are different kinds of machines are manufactured in the industry of Roll Compactor machine. The kinds of Roll Compactor machines are steel purling roll forming machines, stud and track roll forming machines, slitting and cut to length machines, etc. each of the machines come with 2 years or 550 working hours guarantee. IBR sheet roll forming machine is one of them. It has a great value in our daily day life. In the modern life, it is completely unthinkable to live a life without it. It is mainly used in the African market. There are two kinds of IBR sheet former machines and they are IBR686 and IBR890. Whatever we do we need the help of papers and sheets to ensure an agreement of for the sake of fast communication, the help of the sheets is inevitable. To make the sheets there is a sheer need for Roll Compactor Machine and to manufacture them there is a need for machines that create them. To meet the demand, there is a need for such a Machine that would lend help to manufacture them. But what is so important in this matter is to manufacture in a creative and innovative way. It is completely capable of providing that.

The body of the machines is generally created with 36 A3 H beam steel, 45# steel is the materials that are commonly used in the manufacture of the machines. Only materials are not the necessary rather there are other needs for them as to provide enough amount of heat equally important. After they are sent to chroming treatment. Black oxide or blackening treatment is usually provided immediately after the manufacture of the machines. In the industry of Pharmaceutical Machineries, there is a great need of other developed machines which are imported from China basically. Not all kinds of machines and equipment can be helpful in this matter. So the helping machines are picked out carefully.

Summary:

Roll forming machines are huge help making different kinds of machines and to produce innovative and technologically advanced machines to help increase the convenience of life.